I installed twhirl a couple of months ago. Today it stopped working telling me that Adobe Air was broken.
There is nothing on Vista to let me uninstall, repair or otherwise tinker with Air and its applications. I found this timely blog post on uninstall:
Quoted from his email, here’s how you uninstall Adobe AIR if it does not appear in the Add/Remove Programs control panel:
Download the latest installer and then pass it the “-uninstall” flag from the command line, like so:
Worked like a champ.